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Theranostics 11 , 89939008 (2021)

The most robust clinical evidence to date concerns the improvement of muscular and metabolic parameters (strength, endurance, insulin sensitivity) and the modulation of chronic inflammation. A 2024 randomised trial comparing NAD IV with NR IV in healthy adults showed that both modalities increase the available NAD pool, with a favourable safety profile

In the early phase of this disease model, macrophages that produce neuroglia-derived neurotrophic factors can offer protective support to the CNS

It is also a good source of glutathione precursors, such as cysteine and glycine, that help our body produce more of this vital antioxidant